Cutaneous Lymphocyte Antigen 抗体
This anti- antibody is a 大鼠 单克隆 antibody detecting in FACS. Suitable for 人 和 小鼠.
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Quick Overview for Cutaneous Lymphocyte Antigen 抗体 (ABIN2660530)
抗原
Cutaneous Lymphocyte Antigen
适用
人, 小鼠
宿主
大鼠
克隆类型
单克隆
应用范围
Flow Cytometry (FACS)
克隆位点
HECA-452
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纯度
- This antibody is at > 85 % purity.
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亚型
- IgM kappa
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- The antibody solution should be stored undiluted between 2°C and 8°C.
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- Cutaneous Lymphocyte Antigen
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背景
- Cutaneous lymphocyte antigen (CLA) is a 140 kD homodimer protein recognized by a unique mAb, HECA-452. It is expressed on T cells in skin, subsets of peripheral blood memory T cells, NK cells, memory B cells and dendritic cells as well as on monocytes, granulocytes, and activated endothelial cells. CLA is a carbohydrate epitope of sialic acid and fucose-modified P-selectin glycoprotein ligand-1 (PSGL-1), a surface glycoprotein expressed on the majority of peripheral blood leukocytes. CLA is a ligand for E-selectin, P-selectin, and L-selectin. It plays a role in memory lymphocyte homing, tethering, and rolling.
抗原
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